SCHEMBL18436

SCHEMBL18436

Cc1c(Cc2ccc(OCC3(C)CCC(F)(F)CC3)cc2)cccc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 19/20 0.53
SLC5A1 P13866 12/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17829 0.91 SLC5A2 (0.53) SLC5A2SLC5A1
SCHEMBL17983 0.83 SLC5A2 (0.69) SLC5A2SLC5A1
SCHEMBL18170 0.82 SLC5A2 (0.65) SLC5A2SLC5A1
SCHEMBL18273 0.82 SLC5A2 (0.65) SLC5A2SLC5A1
SCHEMBL18452 0.82 SLC5A2 (0.65) SLC5A2SLC5A1
SCHEMBL18014 0.81 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL18219 0.81 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL18772 0.73 SLC5A2 (0.84) SLC5A2SLC5A1
SCHEMBL16572157 0.73 SLC5A2 (0.84) SLC5A2SLC5A1
SCHEMBL18128 0.73 SLC5A2 (0.84) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO claimed