Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17128132 | 1.00 | TP53 (0.34) | TP53PLATHTR2CHTR2BPLG | |
| SCHEMBL21336576 | 0.85 | TP53 (0.35) | TP53HTR2CHTR2B | |
| SCHEMBL18436086 | 0.81 | CHRM2 (0.35) | TP53PLGMAPTKMT2AALDH1A1 | |
| SCHEMBL18436832 | 0.81 | CHRM2 (0.35) | TP53PLGMAPTKMT2AALDH1A1 | |
| SCHEMBL19012448 | 0.78 | KDM4E (0.30) | TP53KMT2AALDH1A1 | |
| SCHEMBL19001146 | 0.78 | KDM4E (0.30) | TP53KMT2AALDH1A1 | |
| SCHEMBL3074193 | 0.77 | NPY5R (0.37) | TP53HTR2CPLGMAPTKMT2A | |
| SCHEMBL3780308 | 0.77 | NPY5R (0.37) | TP53HTR2CPLGMAPTKMT2A | |
| SCHEMBL3069122 | 0.77 | NPY5R (0.37) | TP53HTR2CPLGMAPTKMT2A | |
| SCHEMBL23336239 | 0.74 | TP53 (0.35) | TP53FPR2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-B1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO LTD (CN) | 2019-09-11 | — | — | EP | disclosed |
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |