SCHEMBL18437

SCHEMBL18437

OC[C@H]1O[C@@H](c2cccc(CCc3ccc(OCC4CCC(CF)(CF)CC4)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.57
SLC5A1 P13866 8/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18453 0.83 SLC5A2 (0.60) SLC5A2SLC5A1
SCHEMBL18171 0.83 SLC5A2 (0.60) SLC5A2SLC5A1
SCHEMBL18220 0.83 SLC5A2 (0.74) SLC5A2SLC5A1
SCHEMBL17984 0.83 SLC5A2 (0.67) SLC5A2SLC5A1
SCHEMBL18015 0.83 SLC5A2 (0.74) SLC5A2SLC5A1
SCHEMBL15270405 0.74 SLC5A2 (1.00) SLC5A2
SCHEMBL15298110 0.73 SLC5A2 (0.57) SLC5A2SLC5A1
SCHEMBL13082373 0.71 SLC5A2 (0.86) SLC5A2SLC5A1
SCHEMBL13082853 0.71 SLC5A2 (0.86) SLC5A2SLC5A1
SCHEMBL15820688 0.71 SLC5A2 (0.87) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO claimed