⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318062 | 1.00 | — | — | |
| SCHEMBL5430730 | 1.00 | — | — | |
| SCHEMBL6318074 | 1.00 | — | — | |
| SCHEMBL5430740 | 1.00 | — | — | |
| SCHEMBL13254105 | 0.73 | — | — | |
| SCHEMBL8995817 | 0.73 | — | — | |
| SCHEMBL5021290 | 0.73 | — | — | |
| SCHEMBL13632904 | 0.73 | — | — | |
| SCHEMBL13430314 | 0.73 | — | — | |
| SCHEMBL9556755 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995075-B2 | Process for producing fluorocytosine and fluorocytosine derivatives | UNIVERSITY OF DURHAM | 2021-05-04 | — | — | US | claimed |
| CN-106795123-B | Fluorocytosine and fluorocytosine derivatives | 杜伦大学 | 2021-03-16 | — | — | CN | claimed |
| US-20200095207-A1 | Process for Producing Fluorocytosine and Fluorocytosine Derivatives | UNIVERSITY OF DURHAM (GB) | 2020-03-26 | — | — | US | claimed |
| EP-3186231-B1 | PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES | UNIV DURHAM (GB) | 2019-07-10 | — | — | EP | claimed |
| US-20170298028-A1 | Process for Producing Fluorocytosine and Fluorocytosine Derivatives | UNIVERSITY OF DURHAM (GB) | 2017-10-19 | — | — | US | claimed |
| EP-3186231-A1 | PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES | University of Durham (GB) | 2017-07-05 | — | — | EP | claimed |
| CN-106795123-A | Fluorocytosine and fluorocytosine derivatives | 杜伦大学 | 2017-05-31 | — | — | CN | claimed |
| WO-2016030662-A1 | PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES | UNIVERSITY OF DURHAM (GB) | 2016-03-03 | — | — | WO | claimed |
| US-6903224-B2 | Substituted 1,3-oxathiolanes | BIOCHEM PHARMA INC. (CA) | 2005-06-07 | — | — | US | claimed |
| US-20030087918-A1 | Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 2003-05-08 | — | — | US | claimed |
| US-10995075-B2 | Process for producing fluorocytosine and fluorocytosine derivatives | UNIVERSITY OF DURHAM | 2021-05-04 | — | — | US | disclosed |
| CN-106795123-B | Fluorocytosine and fluorocytosine derivatives | 杜伦大学 | 2021-03-16 | — | — | CN | disclosed |
| US-20200095207-A1 | Process for Producing Fluorocytosine and Fluorocytosine Derivatives | UNIVERSITY OF DURHAM (GB) | 2020-03-26 | — | — | US | disclosed |
| EP-3186231-B1 | PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES | UNIV DURHAM (GB) | 2019-07-10 | — | — | EP | disclosed |
| US-20170298028-A1 | Process for Producing Fluorocytosine and Fluorocytosine Derivatives | UNIVERSITY OF DURHAM (GB) | 2017-10-19 | — | — | US | disclosed |
| US-6518425-B1 | A process for producing a 1,3-oxathiolane nucleoside comprising reacting a 5-halo-2-protected-oxymethyl-1,3-oxathiolane with a silylated purine or pyrimidine without the addition of a Lewis acid or an additional base to the reaction | EMORY UNIVERSITY | 2003-02-11 | — | — | US | disclosed |
| US-6350753-B1 | 2-ACETOXYMETHYL-4-(THYMIN-1'-YL)-1,3,-DIOXOLANE; 2-BENZOYLOXYMETHYL-4-(CYTOSIN-1'-YL)-1,3-DIOXOLANE; ANTIVIRAL AGENTS, PARTICULARY FOR THE TREATMENT OF THE HIV INFECTIONS IN MAMMALS, ESPECIALLY HUMANS | BIOCHEM PHARMA INC. (CA) | 2002-02-26 | — | — | US | disclosed |
| EP-1104415-A1 | METHOD OF MANUFACTURE OF 1,3-OXATHIOLANE NUCLEOSIDES | Triangle Pharmaceuticals Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| US-6215004-B1 | CYCLIZATION OF MERCAPTOACETIC ACID WITH ACETAL IN SOLVENT; SULFIDING | EMORY UNIVERSITY | 2001-04-10 | — | — | US | disclosed |
| WO-2000009494-A1 | METHOD OF MANUFACTURE OF 1,3-OXATHIOLANE NUCLEOSIDES | TRIANGLE PHARMACEUTICALS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |