Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 16/20 | 0.74 |
| ▸ | CLK3 | P49761 | 16/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 16/20 | 0.74 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | WNT1 | P04628 | 2/20 | 0.54 |
| ▸ | ITK | Q08881 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18446260 | 0.94 | CLK2 (0.65) | CLK2CLK3DYRK1ACDK7WNT1 | |
| SCHEMBL18452200 | 0.91 | CLK2 (0.61) | CLK2CLK3DYRK1ACDK7WNT1 | |
| SCHEMBL18484712 | 0.91 | CLK3 (0.78) | CLK2CLK3DYRK1ACDK7WNT1 | |
| SCHEMBL18441939 | 0.90 | CLK2 (0.64) | CLK2CLK3DYRK1ACDK7WNT1 | |
| SCHEMBL18475865 | 0.90 | CLK2 (0.64) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18444391 | 0.90 | CLK2 (0.73) | CLK2CLK3DYRK1ACDK7WNT1 | |
| SCHEMBL18448517 | 0.90 | CLK2 (0.68) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18447812 | 0.90 | CLK3 (0.79) | CLK2CLK3DYRK1ACDK7WNT1 | |
| SCHEMBL18482546 | 0.90 | CLK2 (0.67) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18448952 | 0.89 | CLK3 (0.85) | CLK2CLK3DYRK1ACDK7WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024013-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | claimed |
| WO-2017024013-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |