Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK3 | P49761 | 17/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 17/20 | 0.67 |
| ▸ | CLK2 | P49760 | 16/20 | 0.67 |
| ▸ | ITK | Q08881 | 2/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20454878 | 0.92 | CLK3 (0.69) | CLK3DYRK1ACLK2ITK | |
| SCHEMBL18447281 | 0.89 | CLK2 (0.65) | CLK3DYRK1ACLK2ITKCDK7 | |
| SCHEMBL18451006 | 0.88 | CLK2 (0.55) | CLK3DYRK1ACLK2ITK | |
| SCHEMBL18447614 | 0.85 | CLK2 (0.62) | CLK3DYRK1ACLK2 | |
| SCHEMBL18441732 | 0.85 | CLK2 (0.73) | CLK3DYRK1ACLK2CDK7 | |
| SCHEMBL18448150 | 0.85 | DYRK1A (0.71) | CLK3DYRK1ACLK2 | |
| SCHEMBL18442956 | 0.84 | CLK2 (0.57) | CLK3DYRK1ACLK2ITK | |
| SCHEMBL18484710 | 0.84 | CLK3 (0.66) | CLK3DYRK1ACLK2 | |
| SCHEMBL18447632 | 0.84 | CLK3 (0.65) | CLK3DYRK1ACLK2 | |
| SCHEMBL9904282 | 0.84 | CLK2 (0.62) | CLK3DYRK1ACLK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024013-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | claimed |