Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.81 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11806873 | 0.98 | SRD5A2 (0.79) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| Hydrochloric Acid SCHEMBL11808367 | 0.98 | SRD5A2 (0.79) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL10728165 | 0.90 | SRD5A2 (0.72) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL10081754 | 0.90 | SRD5A2 (1.00) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL8253251 | 0.90 | SRD5A2 (0.68) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL12514876 | 0.89 | SRD5A2 (0.67) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL10442777 | 0.89 | SRD5A2 (1.00) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL1275273 | 0.88 | SRD5A2 (0.66) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL29431442 | 0.88 | SRD5A2 (0.66) | SRD5A2SRD5A1ALDH1A1RAB9AMITF | |
| SCHEMBL27506 | 0.86 | SRD5A2 (0.81) | SRD5A2SRD5A1ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032221-A1 | Polyarylate containing member | XEROX CORPORATION. | 2008-02-07 | — | — | US | claimed |
| EP-0397418-A1 | 9,10-dihydrophenanthrene-2,7-dicarboxylic acid diesters, 7-Bromo-9,10-dihydrophenanthrene-2-carboxylic acid esters and a process for producing the same | Director General, Agency of Industrial Science and Technology (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-1467969-B1 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIV STRATHCLYDE (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-7700765-B2 | DNA minor groove binding compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2010-04-20 | — | — | US | disclosed |
| US-7534536-B2 | Photoconductor containing substrate, undercoat layer thereover comprising polyol resin, aminoplast resin, polyarylate, siloxane modified polyarylate, epoxy modified polyarylate, or urethane modified polyarylate, or amine modified polyarylate, metal oxide, photogenerating layer, and charge transport layer | XEROX CORPORATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080032221-A1 | Polyarylate containing member | XEROX CORPORATION. | 2008-02-07 | — | — | US | disclosed |
| US-20070117760-A1 | Dna minor groove binding compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2007-05-24 | — | — | US | disclosed |
| EP-1467969-A2 | DNA MINOR GROOVE BINDING COMPOUNDS | The University of Strathclyde (GB) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059881-A2 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2003-07-24 | — | — | WO | disclosed |
| WO-2001019792-A1 | COVALENTLY LINKED DIMERIC DNA BINDING MOLECULES | GENELABS TECHNOLOGIES, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| EP-0397418-A1 | 9,10-dihydrophenanthrene-2,7-dicarboxylic acid diesters, 7-Bromo-9,10-dihydrophenanthrene-2-carboxylic acid esters and a process for producing the same | Director General, Agency of Industrial Science and Technology (JP) | 1990-11-14 | — | — | EP | disclosed |
| EP-0397418-A1 | 9,10-dihydrophenanthrene-2,7-dicarboxylic acid diesters, 7-Bromo-9,10-dihydrophenanthrene-2-carboxylic acid esters and a process for producing the same | Director General, Agency of Industrial Science and Technology (JP) | 1990-11-14 | — | — | EP | disclosed |
| EP-0397418-A1 | 9,10-dihydrophenanthrene-2,7-dicarboxylic acid diesters, 7-Bromo-9,10-dihydrophenanthrene-2-carboxylic acid esters and a process for producing the same | Director General, Agency of Industrial Science and Technology (JP) | 1990-11-14 | — | — | EP | disclosed |
| US-3931211-A | OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117760-A1 | Dna minor groove binding compounds | PCNA, POLL, POLM | SRD5A2 1819/4885SRD5A1 1329/4885ALDH1A1 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.