SCHEMBL18453262

SCHEMBL18453262

NC1(N)c2cccnc2-c2ncccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.40
KMT2A Q03164 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
MEN1 O00255 2/20 0.39
BLM P54132 2/20 0.39
TDP2 O95551 2/20 0.39
NSD2 O96028 2/20 0.39
PAX8 Q06710 2/20 0.39
ABL1 P00519 1/20 0.39
PLCG1 P19174 1/20 0.39
CES1 P23141 1/20 0.39
RIN1 Q13671 1/20 0.39
THRB P10828 1/20 0.39
GAA P10253 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 2/20 0.37
S100A4 P26447 3/20 0.35
PTPRC P08575 2/20 0.35
CDC25B P30305 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11990870 0.79 PDK2 (0.42) PDK2KMT2ATDP1MEN1BLM
SCHEMBL1335900 0.75 PDK2 (0.43) PDK2KMT2ATDP1MEN1BLM
SCHEMBL22424774 0.75 PDK2 (0.40) PDK2KMT2ATDP1MEN1BLM
SCHEMBL2133128 0.71 PDK2 (0.46) PDK2KMT2ATDP1MEN1BLM
SCHEMBL19622963 0.71 PDK2 (0.37) PDK2KMT2AMEN1BLMGAA
SCHEMBL32682807 0.70 PDK2 (0.49) PDK2KMT2ATDP1MEN1BLM
SCHEMBL5344736 0.70 PDK2 (0.49) PDK2KMT2ATDP1MEN1BLM
SCHEMBL29419598 0.70 PDK2 (0.49) PDK2KMT2ATDP1MEN1BLM
SCHEMBL15705971 0.70 KMT2A (0.51) PDK2KMT2ATDP1MEN1BLM
SCHEMBL23125641 0.67 PDK2 (0.49) PDK2KMT2ATDP1BLMTDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351576-B1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2020-05-06 EP disclosed
EP-3351576-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company Limited (JP) 2018-07-25 EP disclosed
EP-3124518-A1 POLYMER COMPOUND, AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company Limited (JP) 2017-02-01 EP disclosed