Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18455133 | 0.94 | CHRNB4 (0.47) | CHRNB4CHRNA3 | |
| SCHEMBL23023340 | 0.84 | CYP1A2 (0.52) | CYP1A2CHRNB4CHRNA3 | |
| SCHEMBL96731 | 0.84 | CYP1A2 (0.52) | CYP1A2CHRNB4CHRNA3 | |
| SCHEMBL23640635 | 0.84 | CYP1A2 (0.52) | CYP1A2CHRNB4CHRNA3 | |
| SCHEMBL25962289 | 0.81 | CYP1A2 (0.48) | CYP1A2CHRNB4CHRNA3 | |
| SCHEMBL15806843 | 0.81 | CYP1A2 (0.48) | CYP1A2CHRNB4CHRNA3 | |
| SCHEMBL2459458 | 0.80 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL12886592 | 0.79 | CHRNB4 (0.47) | CHRNB4CHRNA3 | |
| SCHEMBL96320 | 0.78 | — | — | |
| SCHEMBL88569 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771324-B1 | MYXOVIRUS THERAPEUTICS, COMPOUNDS, AND USES RELATED THERETO | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |