Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239695 | 0.94 | — | — | |
| SCHEMBL14651377 | 0.88 | — | — | |
| Propane SCHEMBL11542346 | 0.86 | — | — | |
| SCHEMBL9906194 | 0.84 | CA12 (0.43) | CA12CA7CA14NPSR1HRH4 | |
| SCHEMBL10001929 | 0.84 | CA12 (0.43) | CA12CA7CA14NPSR1HRH4 | |
| SCHEMBL4622 | 0.81 | — | — | |
| SCHEMBL20614479 | 0.81 | CA12 (0.45) | CA12CA7CA14NPSR1HRH4 | |
| SCHEMBL1221354 | 0.81 | — | — | |
| SCHEMBL2123718 | 0.81 | CA12 (0.45) | CA12CA7CA14NPSR1HRH4 | |
| SCHEMBL10001930 | 0.81 | CA12 (0.45) | CA12CA7CA14NPSR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017020010-A1 | BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION | NEUROPORE THERAPIES, INC. (US) | 2017-02-02 | — | — | WO | disclosed |