Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457891 | 0.91 | GRM2 (0.52) | GRM2KCNH2GRM5 | |
| SCHEMBL18457681 | 0.89 | GRM2 (0.67) | GRM2KCNH2 | |
| SCHEMBL18458006 | 0.81 | GRM2 (0.59) | GRM2KCNH2 | |
| SCHEMBL18457893 | 0.80 | GRM2 (0.67) | GRM2KCNH2 | |
| SCHEMBL25859202 | 0.77 | GRM2 (0.53) | GRM2KCNH2 | |
| SCHEMBL25859256 | 0.77 | GRM2 (0.53) | GRM2KCNH2 | |
| SCHEMBL22622618 | 0.74 | GRM2 (0.53) | GRM2KCNH2 | |
| SCHEMBL17485443 | 0.72 | GRM2 (0.67) | GRM2KCNH2 | |
| SCHEMBL18458178 | 0.72 | GRM2 (0.60) | GRM2KCNH2 | |
| SCHEMBL22950492 | 0.71 | GRM2 (0.47) | GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017018475-A1 | CONDENSED PYRAZOLE DERIVATIVE HAVING NEW LINKER SITE AND MEDICINAL USE OF SAME | 大日本住友製薬株式会社 | 2017-02-02 | — | — | WO | disclosed |