SCHEMBL1845820

SCHEMBL1845820

FC(F)(F)C(F)(F)c1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19405441 0.86
SCHEMBL1843525 0.86 ELANE (0.31)
SCHEMBL19405451 0.86
SCHEMBL1843889 0.85 MAPT (0.33)
SCHEMBL19405512 0.83
SCHEMBL4585416 0.83 MAPT (0.33)
SCHEMBL1845842 0.83 MAPT (0.33)
SCHEMBL1842947 0.83 MAPT (0.33)
SCHEMBL4584818 0.83 MAPT (0.33)
SCHEMBL4585006 0.83 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024430-A Bipyrimidine fluorene compound, organic electroluminescent element and consumer product 浙江八亿时空先进材料有限公司 2023-11-10 CN claimed
CN-114907361-A Trimeric heterocyclic derivative and application thereof 北京八亿时空液晶科技股份有限公司 2022-08-16 CN claimed
CN-111253611-B PET foaming method 上海越科新材料股份有限公司 2022-07-05 CN claimed
CN-114256431-A Material for organic electroluminescent element, and consumer product 上海八亿时空先进材料有限公司 2022-03-29 CN claimed
CN-114213409-A Material for organic electroluminescent element, and consumer product 上海八亿时空先进材料有限公司 2022-03-22 CN claimed
CN-111253611-A PET foaming method 上海越科新材料股份有限公司 2020-06-09 CN claimed
EP-1805141-B1 PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE MERCK SHARP & DOHME (GB) 2010-01-20 EP claimed
US-7638629-B2 Piperidines and related compounds for treatment of alzheimer's disease Merck Sharp & Dohme Ltd, (GB) 2009-12-29 US claimed
US-20080021043-A1 Piperidines and Related Compounds for Treatment of Alzheimer's Disease MERCK SHARP & DOHME LTD. (GB) 2008-01-24 US claimed
EP-1805141-A1 PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE MERCK SHARP &amp; DOHME LTD. (GB) 2007-07-11 EP claimed
US-20060076537-A1 Rhenium compounds ISIS INNOVATION LIMITED (GB) 2006-04-13 US claimed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO claimed
EP-1487937-A2 RHENIUM COMPOUNDS AND THEIR USE IN ELECTROLUMINESCENT DEVICES ISIS INNOVATION LIMITED (GB) 2004-12-22 EP claimed
WO-2003079737-A2 RHENIUM COMPOUNDS AND THEIR USE IN ELECTROLUMINESCENT VORRICHTUNGEN ISIS INNOVATION LIMITED (GB) 2003-09-25 WO claimed
US-20030050314-A1 Novel cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists AVENTIS PHARMA S.A. 2003-03-13 US claimed
EP-0885215-A1 NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS Abbott Laboratories (US) 1998-12-23 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed
WO-1997030045-A1 NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 1997-08-21 WO claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed