SCHEMBL18459127

SCHEMBL18459127

CCC(N)c1ccc(-c2ccc(-c3cc(F)c(F)c(F)c3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC6A4 P31645 1/20 0.46
▸ ANPEP P15144 16/20 0.42
▸ DPP4 P27487 2/20 0.40
▸ CYP17A1 P05093 1/20 0.40
▸ DPP8 Q6V1X1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458616 0.94 SLC6A4 (0.41) SLC6A4ANPEPDPP4CYP17A1DPP8
SCHEMBL18458826 0.89 AKR1C3 (0.41) SLC6A4ANPEPDPP4CYP17A1DPP8
SCHEMBL18458747 0.89 AKR1C3 (0.41) SLC6A4ANPEPDPP4CYP17A1DPP8
SCHEMBL21784989 0.86 SLC6A4 (0.46) SLC6A4DPP4CYP17A1DPP8
SCHEMBL19098119 0.85 MAOB (0.36) SLC6A4ANPEPDPP4CYP17A1DPP8
SCHEMBL19098079 0.85 MAOB (0.36) SLC6A4ANPEPDPP4CYP17A1DPP8
SCHEMBL18458598 0.83 SLC6A4 (0.41) SLC6A4DPP4CYP17A1DPP8
SCHEMBL14383027 0.81 SLC6A4 (0.41) SLC6A4DPP4
SCHEMBL21919623 0.80 ANPEP (0.43) ANPEPCYP17A1
SCHEMBL19097883 0.79 F10 (0.34) ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 — — US disclosed
EP-3450523-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2021-01-06 — — EP disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 — — US disclosed
US-20200172811-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2020-06-04 — — US disclosed
US-10414979-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-17 — — US disclosed
US-10400168-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-03 — — US disclosed
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 — — US disclosed
US-20190203120-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2019-07-04 — — US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 — — US disclosed
US-10208250-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-02-19 — — US disclosed
EP-2883938-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2017-10-25 — — EP disclosed
US-20170255048-A1 LIQUID-CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-09-07 — — US disclosed
US-20170226420-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-10 — — US disclosed
US-20170210986-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-07-27 — — US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 — — US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 — — US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 — — US disclosed
EP-2781578-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2017-03-01 — — EP disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 — — US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 — — US disclosed
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