Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13837243 | 0.87 | TLR7 (0.71) | TLR7TLR8 | |
| SCHEMBL18460251 | 0.82 | TLR7 (0.70) | TLR7TLR8 | |
| SCHEMBL19345053 | 0.81 | TLR7 (0.72) | TLR7TLR8 | |
| SCHEMBL18459755 | 0.81 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL18459754 | 0.81 | TLR7 (0.77) | TLR7TLR8 | |
| SCHEMBL18460250 | 0.79 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL18459929 | 0.78 | TLR7 (0.58) | TLR7TLR8 | |
| SCHEMBL20152970 | 0.78 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL20152936 | 0.78 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL18459886 | 0.77 | TLR7 (0.80) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208037-B2 | Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds | THE UNIVERSITY OF KANSAS (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180134701-A1 | TOLL-LIKE RECEPTOR-7 AND -8 MODULATORY 1H IMIDAZOQUINOLINE DERIVED COMPOUNDS | THE UNIVERSITY OF KANSAS | 2018-05-17 | — | — | US | disclosed |
| US-20170260184-A1 | TOLL-LIKE RECEPTOR-7 AND -8 MODULATORY 1H IMIDAZOQUINOLINE DERIVED COMPOUNDS | UNIV KANSAS (US) | 2017-09-14 | — | — | US | disclosed |
| US-20170029421-A1 | TOLL-LIKE RECEPTOR-7 AND -8 MODULATORY 1H IMIDAZOQUINOLINE DERIVED COMPOUNDS | UNIV KANSAS (US) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134701-A1 | TOLL-LIKE RECEPTOR-7 AND -8 MODULATORY 1H IMIDAZOQUINOLINE DERIVED COMPOUNDS | TLR7, TLR8, TLR3 | TLR7 1/4885TLR8 2/4885 |
| US-20170029421-A1 | TOLL-LIKE RECEPTOR-7 AND -8 MODULATORY 1H IMIDAZOQUINOLINE DERIVED COMPOUNDS | TLR7, TLR8, TLR3 | TLR7 1/4885TLR8 2/4885 |
| US-10208037-B2 | Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds | TLR7, TLR8, TLR3 | TLR7 1/4885TLR8 2/4885 |
| US-20170260184-A1 | TOLL-LIKE RECEPTOR-7 AND -8 MODULATORY 1H IMIDAZOQUINOLINE DERIVED COMPOUNDS | TLR7, TLR8, TLR3 | TLR7 1/4885TLR8 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.