Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468377 | 1.00 | AAK1 (0.50) | AAK1SCN10A | |
| SCHEMBL18483091 | 0.86 | AAK1 (0.41) | AAK1SCN10A | |
| SCHEMBL15116794 | 0.86 | AAK1 (0.57) | AAK1SCN10A | |
| SCHEMBL19388413 | 0.86 | AAK1 (0.57) | AAK1SCN10A | |
| SCHEMBL15125224 | 0.81 | AAK1 (0.54) | AAK1SCN10A | |
| SCHEMBL20468458 | 0.77 | AAK1 (0.52) | AAK1SCN10A | |
| SCHEMBL18482559 | 0.77 | AAK1 (0.46) | AAK1SCN10A | |
| SCHEMBL15116605 | 0.76 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL15116788 | 0.76 | AAK1 (0.48) | AAK1SCN10A | |
| SCHEMBL19388627 | 0.76 | AAK1 (0.48) | AAK1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023631-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-09 | — | — | WO | disclosed |