Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.37 |
| ▸ | SCN1A | P35498 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205811 | 0.87 | SCN1A (0.41) | PIK3CDSCN1ASCN5ASCN8ATNF | |
| SCHEMBL19205810 | 0.87 | SCN1A (0.41) | PIK3CDSCN1ASCN5ASCN8ATNF | |
| SCHEMBL19205792 | 0.81 | PIK3CD (0.39) | PIK3CDSCN1ASCN5ASCN8AKDM4E | |
| SCHEMBL18484164 | 0.81 | PIK3CD (0.39) | PIK3CDSCN1ASCN5ASCN8AKDM4E | |
| SCHEMBL18484176 | 0.73 | TNF (0.41) | PIK3CDSCN1ASCN5ASCN8ATNF | |
| SCHEMBL18484178 | 0.73 | TNF (0.41) | PIK3CDSCN1ASCN5ASCN8ATNF | |
| SCHEMBL19205602 | 0.72 | CYP2C19 (0.46) | PIK3CDSCN1ASCN5ASCN8AKDM4E | |
| SCHEMBL18483511 | 0.72 | CYP2C19 (0.46) | PIK3CDSCN1ASCN5ASCN8AKDM4E | |
| SCHEMBL19205663 | 0.70 | SOS1 (0.39) | PIK3CDSCN1ASCN5ASCN8ATNF | |
| SCHEMBL19205662 | 0.70 | SOS1 (0.39) | PIK3CDSCN1ASCN5ASCN8ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |