Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK3 | P49761 | 20/20 | 0.82 |
| ▸ | DYRK1A | Q13627 | 20/20 | 0.82 |
| ▸ | CLK2 | P49760 | 19/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18485091 | 0.91 | CLK2 (0.68) | CLK3DYRK1ACLK2 | |
| SCHEMBL20455121 | 0.90 | CLK2 (1.00) | CLK3DYRK1ACLK2 | |
| SCHEMBL18487682 | 0.85 | CLK2 (0.60) | CLK3DYRK1ACLK2 | |
| SCHEMBL20454687 | 0.85 | CLK2 (0.78) | CLK3DYRK1ACLK2 | |
| SCHEMBL18487003 | 0.85 | CLK2 (0.69) | CLK3DYRK1ACLK2 | |
| SCHEMBL18487120 | 0.84 | CLK2 (0.61) | CLK3DYRK1ACLK2 | |
| SCHEMBL18480331 | 0.84 | CLK2 (0.71) | CLK3DYRK1ACLK2 | |
| SCHEMBL18490002 | 0.84 | CLK2 (0.59) | CLK3DYRK1ACLK2 | |
| SCHEMBL20455063 | 0.83 | CLK2 (0.77) | CLK3DYRK1ACLK2 | |
| SCHEMBL20454740 | 0.83 | CLK2 (0.82) | CLK3DYRK1ACLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024010-A1 | 3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |