Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.51 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.47 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.45 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720055 | 0.90 | MAP2K1 (0.46) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL5555654 | 0.84 | MAP2K1 (0.57) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2720047 | 0.83 | MAP2K1 (0.64) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2718739 | 0.82 | MAP2K1 (0.49) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2718701 | 0.81 | MAP2K1 (0.52) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2719691 | 0.80 | MAP2K1 (0.50) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2362783 | 0.80 | MAP2K1 (0.57) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL2718749 | 0.79 | MAP2K1 (0.51) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL3010504 | 0.79 | MAP2K1 (0.58) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL10118289 | 0.79 | MAP2K1 (0.48) | MAP2K1MAP2K2MAP2K5EIF2AK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635587-B1 | 6-ARYLAMINO PYRIDONE CARBOXAMIDE AS MEK INHIBITORS | CENTAURUS BIOPHARMA CO LTD (CN) | 2017-02-15 | — | — | EP | disclosed |