Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849160 | 0.89 | GCK (0.75) | GCKKCNH2 | |
| SCHEMBL1850319 | 0.87 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL1850612 | 0.86 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL1846810 | 0.86 | GCK (0.73) | GCKKCNH2 | |
| SCHEMBL1845612 | 0.85 | GCK (0.63) | GCKKCNH2 | |
| SCHEMBL838018 | 0.84 | GCK (0.84) | GCKKCNH2 | |
| SCHEMBL1849500 | 0.84 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL1848586 | 0.81 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL1850658 | 0.80 | GCK (0.75) | GCKKCNH2 | |
| SCHEMBL839598 | 0.80 | KCNH2 (0.81) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324028-A2 | THERAPEUTIC AGENTS 414 | AstraZeneca AB (SE) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010015849-A2 | THERAPEUTIC AGENTS 414 | ASTRAZENECA AB (SE) | 2010-02-11 | — | — | WO | disclosed |