SCHEMBL18489461

SCHEMBL18489461

CC(C)(C)c1ccc(O)c(C=Nc2ccccc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
ALDH1A1 P00352 4/20 0.56
MEN1 O00255 2/20 0.56
GAA P10253 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 2/20 0.56
PKM P14618 1/20 0.56
SIRT2 Q8IXJ6 1/20 0.50
MAOB P27338 4/20 0.46
MAOA P21397 1/20 0.46
POLB P06746 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TSHR P16473 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23644527 1.00 MAPT (0.64) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL12657762 0.86 MAPT (0.66) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL17191770 0.83 MAPT (0.66) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL16114890 0.82 CA1 (0.59) MAPTSMN1; SMN2ALDH1A1MEN1GAA
Acetic Acid SCHEMBL1229036 0.82 MAPT (0.57) MAPTSMN1; SMN2ALDH1A1MEN1GAA
Acetic Acid SCHEMBL1229490 0.82 MAPT (0.54) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL5681161 0.82 MAPT (0.60) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL5681158 0.82 MAPT (0.60) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL18489435 0.80 MAPT (0.62) MAPTSMN1; SMN2ALDH1A1MEN1GAA
SCHEMBL17191759 0.80 MAPT (0.62) MAPTSMN1; SMN2ALDH1A1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US claimed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US claimed
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP disclosed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US disclosed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP disclosed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US disclosed