Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 12/20 | 0.56 |
| ▸ | JAK3 | P52333 | 11/20 | 0.56 |
| ▸ | JAK2 | O60674 | 6/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | TYK2 | P29597 | 3/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15086982 | 0.82 | JAK3 (0.62) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL20343713 | 0.79 | JAK1 (0.59) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL18493479 | 0.79 | JAK3 (0.59) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL26500579 | 0.77 | CSF1R (0.67) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL22061391 | 0.75 | CSF1R (0.65) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL14342248 | 0.75 | JAK3 (0.54) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL3534102 | 0.73 | JAK3 (0.97) | JAK1JAK3JAK2TYK2 | |
| SCHEMBL13007800 | 0.73 | JAK1 (0.53) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL20597179 | 0.73 | TNNI3K (0.54) | JAK1JAK3JAK2CSF1RTYK2 | |
| SCHEMBL29518010 | 0.73 | TNNI3K (0.54) | JAK1JAK3JAK2CSF1RTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044171-A1 | COMPOUNDS FOR PREPARING PYRROLE SIX-MEMBERED HETEROARYL RING DERIVATIVE | JIANGSU HENGRUI MEDICINE CO (CN) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044171-A1 | COMPOUNDS FOR PREPARING PYRROLE SIX-MEMBERED HETEROARYL RING DERIVATIVE | JAK2, JAK1, JAK3 | JAK1 2/4885JAK3 3/4885JAK2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.