Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 12/20 | 0.70 |
| ▸ | CLK3 | P49761 | 11/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.70 |
| ▸ | WNT1 | P04628 | 8/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18444049 | 0.94 | CLK2 (0.80) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18447303 | 0.88 | CLK2 (0.71) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18494264 | 0.86 | CLK2 (0.76) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL20965119 | 0.86 | CLK2 (0.83) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL20422888 | 0.86 | CLK2 (0.69) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18446114 | 0.86 | CLK2 (0.66) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18494614 | 0.86 | CLK2 (0.82) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18494607 | 0.85 | CLK2 (0.84) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18494222 | 0.85 | CLK2 (0.84) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL18495037 | 0.85 | CLK2 (0.84) | CLK2CLK3DYRK1AWNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024026-A1 | 3-(1H-INDOL-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2017-02-09 | — | — | WO | disclosed |