Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497702 | 1.00 | IRAK4 (0.79) | IRAK4 | |
| SCHEMBL18497776 | 0.95 | IRAK4 (0.80) | IRAK4 | |
| SCHEMBL24249992 | 0.93 | IRAK4 (0.74) | IRAK4 | |
| SCHEMBL18497844 | 0.90 | IRAK4 (0.76) | IRAK4 | |
| SCHEMBL18497805 | 0.90 | IRAK4 (0.76) | IRAK4 | |
| SCHEMBL18525508 | 0.90 | IRAK4 (0.76) | IRAK4 | |
| SCHEMBL30196528 | 0.89 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL30196601 | 0.89 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17137265 | 0.89 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL24250147 | 0.89 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | claimed |
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |