Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.72 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.65 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.65 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.65 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.65 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.65 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.64 |
| ▸ | RET | P07949 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | TDO2 | P48775 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395411 | 0.86 | LRRK2 (0.76) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1395409 | 0.86 | LRRK2 (0.76) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5468623 | 0.84 | LRRK2 (0.71) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5474728 | 0.84 | LRRK2 (0.75) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5468627 | 0.84 | LRRK2 (0.71) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3804991 | 0.84 | LRRK2 (0.75) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3749415 | 0.84 | LRRK2 (0.74) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5474727 | 0.84 | LRRK2 (0.75) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5477805 | 0.84 | LRRK2 (0.83) | LRRK2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5477806 | 0.84 | LRRK2 (0.83) | LRRK2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567305-B2 | Quinoxaline compounds and derivatives | SOUTHERN METHODIST UNIVERSITY (US) | 2017-02-14 | — | — | US | disclosed |