Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350765 | 0.82 | MEN1 (0.62) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL10914798 | 0.82 | MEN1 (0.62) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL20888511 | 0.81 | KMT2A (0.41) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL12368473 | 0.80 | MEN1 (0.61) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL20888509 | 0.79 | MEN1 (0.40) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL9331659 | 0.78 | UGT2B7 (0.56) | MEN1KMT2AKDM4ELMNAUGT2B7 | |
| SCHEMBL2812852 | 0.78 | UGT2B7 (0.56) | MEN1KMT2AKDM4ELMNAUGT2B7 | |
| SCHEMBL9331663 | 0.78 | UGT2B7 (0.56) | MEN1KMT2AKDM4ELMNAUGT2B7 | |
| SCHEMBL9334664 | 0.78 | UGT2B7 (0.56) | MEN1KMT2AKDM4ELMNAUGT2B7 | |
| SCHEMBL18355736 | 0.77 | MEN1 (0.57) | MEN1KMT2AKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566276-B2 | Phthalazinone derivatives | KUDOS PHARMACEUTICALS LIMITED (GB) | 2017-02-14 | — | — | US | disclosed |