SCHEMBL18503069

SCHEMBL18503069

C=CC(=O)OCCCCCCOC(=O)C1CCC(CCCCC)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
HPGD P15428 1/20 0.53
ALDH1A1 P00352 1/20 0.49
CYP3A4 P08684 1/20 0.49
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
HCAR2 Q8TDS4 2/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.40
NAAA Q02083 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
CCR2 P41597 1/20 0.37
ATM Q13315 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19623999 0.99 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL13400991 0.99 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL3478345 0.96 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL18699716 0.96 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL13400995 0.96 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL3477457 0.93 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL21558864 0.92 TSHR (0.45) TSHRHPGDALDH1A1CYP3A4MEN1
SCHEMBL3478263 0.91 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL16133529 0.91 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL13400992 0.88 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170044436-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 US disclosed
US-20170044436-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 US disclosed