SCHEMBL18503371

SCHEMBL18503371

Cc1ccc(-c2ccc(C3CCC(C)CC3)cc2)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.45
CYP2C9 P11712 2/20 0.45
APP P05067 2/20 0.45
ESR2 Q92731 1/20 0.45
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
FASN P49327 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDE3B Q13370 2/20 0.36
PDE3A Q14432 2/20 0.36
KDM1A O60341 1/20 0.34
PRKAB2 O43741 1/20 0.33
PRKAG1 P54619 1/20 0.33
PRKAA2 P54646 1/20 0.33
PRKAA1 Q13131 1/20 0.33
PRKAG3 Q9UGI9 1/20 0.33
PRKAG2 Q9UGJ0 1/20 0.33
PRKAB1 Q9Y478 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19820867 0.92 FASN (0.41) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL19493506 0.91 CYP3A4 (0.43) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL802781 0.91 CYP3A4 (0.43) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL2741531 0.91 FASN (0.47) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL91987 0.91 FASN (0.47) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL19820861 0.91 FASN (0.40) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL13408581 0.90 FASN (0.46) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL12377041 0.89 FASN (0.49) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL19820869 0.89 FASN (0.39) CYP3A4CYP2C9APPESR2CYP2D6
SCHEMBL19820868 0.88 FASN (0.44) CYP3A4CYP2C9APPESR2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587175-B2 Nematic liquid crystal composition DIC CORPORATION (JP) 2017-03-07 US disclosed
US-20170045765-A1 LCD DEVICE DIC CORPORATION (JP) 2017-02-16 US disclosed