SCHEMBL18504674

SCHEMBL18504674

O=C(Cl)c1cccc(C(F)F)c1COc1ccn(O)n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.33
NR1H4 Q96RI1 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18503083 0.89 NR1H4 (0.36) KLKB1NR1H4
SCHEMBL18504783 0.88 PARP1 (0.32) KLKB1NR1H4
SCHEMBL18504475 0.88 KLKB1 (0.33) KLKB1NR1H4
SCHEMBL18504708 0.88 NR1H4 (0.37) NR1H4
SCHEMBL18504612 0.88 KLKB1 (0.35) KLKB1NR1H4
SCHEMBL22564260 0.87 KLKB1 (0.32) KLKB1NR1H4
SCHEMBL18504522 0.86 KDM4E (0.36) KLKB1
SCHEMBL18504844 0.86 KLKB1 (0.33) KLKB1
SCHEMBL18504624 0.84 TSHR (0.39)
SCHEMBL18504976 0.84 MAPT (0.36) KLKB1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed