Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807231 | 0.92 | DPP4 (0.49) | DPP4KDM2B | |
| SCHEMBL19807288 | 0.92 | DPP4 (0.49) | DPP4KDM2B | |
| SCHEMBL19807242 | 0.92 | DPP4 (0.45) | DPP4KDM2B | |
| SCHEMBL19807262 | 0.92 | DPP4 (0.49) | DPP4KDM2B | |
| SCHEMBL19807241 | 0.92 | DPP4 (0.45) | DPP4KDM2B | |
| SCHEMBL20976145 | 0.92 | DPP4 (0.45) | DPP4KDM2B | |
| SCHEMBL19799063 | 0.83 | KDM2B (0.38) | DPP4KDM2BKDM4EALDH1A1ALOX15 | |
| SCHEMBL19799017 | 0.83 | KDM2B (0.38) | DPP4KDM2BKDM4EALDH1A1ALOX15 | |
| SCHEMBL21120617 | 0.83 | KDM2B (0.38) | DPP4KDM2BKDM4EALDH1A1ALOX15 | |
| SCHEMBL19799062 | 0.83 | KDM2B (0.38) | DPP4KDM2BKDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130592-A1 | ANALOGUES OF 4H-PYRAZOLO[1,5- ]BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-02-15 | — | — | EP | disclosed |