SCHEMBL18506941

SCHEMBL18506941

CC(N)C(C)B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.64
LAP3 P28838 3/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20155898 1.00 ANPEP (0.64) ANPEPLAP3
SCHEMBL18851740 0.85 ANPEP (0.58) ANPEPLAP3
SCHEMBL22103066 0.83 ANPEP (0.60) ANPEPLAP3
SCHEMBL21190520 0.83 ANPEP (0.60) ANPEPLAP3
SCHEMBL23969659 0.78 ANPEP (0.55) ANPEPLAP3
SCHEMBL10592383 0.78 ANPEP (1.00) ANPEPLAP3
SCHEMBL16526079 0.78 ANPEP (0.55) ANPEPLAP3
SCHEMBL12609422 0.78 ANPEP (1.00) ANPEPLAP3
SCHEMBL22667059 0.74 ANPEP (0.50) ANPEPLAP3
SCHEMBL20510145 0.74 ANPEP (0.64) ANPEPLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11242346-B2 Mechanistic target of rapamycin signaling pathway inhibitors and therapeutic applications thereof SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) 2022-02-08 US disclosed
US-20200181147-A1 MECHANISTIC TARGET OF RAPAMYCIN SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) 2020-06-11 US disclosed
US-9714259-B2 Compositions and methods for improving glucose uptake BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2017-07-25 US disclosed
US-20170044189-A1 COMPOSITIONS AND METHODS FOR IMPROVING GLUCOSE UPTAKE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2017-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11242346-B2 Mechanistic target of rapamycin signaling pathway inhibitors and therapeutic applications thereof MTOR, RPTOR, RICTOR ANPEP 3766/4885LAP3 3501/4885
US-20170044189-A1 COMPOSITIONS AND METHODS FOR IMPROVING GLUCOSE UPTAKE SLC2A3, SLC2A4, SLC2A2 ANPEP 2821/4885LAP3 1736/4885
US-20200181147-A1 MECHANISTIC TARGET OF RAPAMYCIN SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF MTOR, RPTOR, RICTOR ANPEP 3766/4885LAP3 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.