Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184635 | 0.81 | GCK (0.75) | GCKLMNAKMT2A | |
| SCHEMBL184841 | 0.80 | GCK (0.75) | GCKKMT2A | |
| SCHEMBL185060 | 0.79 | GCK (0.73) | GCKKMT2A | |
| SCHEMBL185150 | 0.79 | GCK (0.71) | GCKKMT2A | |
| SCHEMBL184750 | 0.79 | GCK (0.66) | GCKLMNARXFP1KMT2ATP53 | |
| SCHEMBL3779285 | 0.79 | GCK (0.70) | GCKKMT2A | |
| SCHEMBL184721 | 0.79 | GCK (1.00) | GCKKMT2A | |
| SCHEMBL184257 | 0.78 | GCK (0.73) | GCKKMT2A | |
| SCHEMBL185438 | 0.78 | GCK (0.65) | GCKLMNARXFP1KMT2ATP53 | |
| SCHEMBL185123 | 0.78 | GCK (0.73) | GCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | claimed |
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |