Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 7/20 | 0.46 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392216 | 0.82 | CMA1 (0.64) | CMA1CTSGHTR2CHTR2BHTR2A | |
| SCHEMBL20119869 | 0.82 | HTR2C (0.63) | CMA1CTSGKDM4EHTR2CHTR2B | |
| SCHEMBL18509533 | 0.81 | MCL1 (0.51) | CMA1CTSGHTR2CHTR2BHTR2A | |
| SCHEMBL18509674 | 0.81 | CMA1 (0.47) | CMA1CTSGKDM4EHTR2CHTR2B | |
| SCHEMBL20120027 | 0.81 | CMA1 (0.47) | CMA1CTSGKDM4EHTR2CHTR2B | |
| SCHEMBL18509797 | 0.81 | CMA1 (0.47) | CMA1CTSGKDM4EHTR2CHTR2B | |
| SCHEMBL18509808 | 0.80 | PTGER1 (0.50) | CMA1CTSGKDM4EHTR2CHTR2B | |
| SCHEMBL18509795 | 0.78 | HTR2C (0.50) | CMA1CTSGKDM4EHTR2CHTR2B | |
| SCHEMBL18509904 | 0.78 | CMA1 (0.41) | CMA1CTSGKDM4EEGFRMEN1 | |
| SCHEMBL18029079 | 0.78 | MAPT (0.46) | CMA1CTSGKDM4EHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | disclosed |