Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.60 |
| ▸ | PRKCG | P05129 | 2/20 | 0.60 |
| ▸ | PRKCB | P05771 | 2/20 | 0.60 |
| ▸ | PRKCA | P17252 | 2/20 | 0.60 |
| ▸ | PRKCH | P24723 | 2/20 | 0.60 |
| ▸ | PRKCI | P41743 | 2/20 | 0.60 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.60 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.60 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.58 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.58 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401638 | 0.88 | PRKD3 (0.72) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL18510371 | 0.87 | LPAR1 (0.58) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL18519898 | 0.84 | PRKD3 (0.68) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL14842644 | 0.84 | PRKD3 (0.68) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL14843034 | 0.84 | PRKD3 (0.68) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7032675 | 0.84 | PRKD3 (0.68) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL14843018 | 0.82 | PRKD3 (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL19214078 | 0.81 | PRKD3 (0.51) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL14587065 | 0.80 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL14012981 | 0.80 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME LLC (US) | 2023-06-27 | — | — | US | disclosed |
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | PRKD3 383/4885PRKCG 1767/4885PRKCB 1771/4885 |
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | PRKD3 393/4885PRKCG 1902/4885PRKCB 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.