Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7639809 | 1.00 | — | — | |
| Bromide SCHEMBL28193270 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL17260895 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL1586512 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6914388 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL15668453 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL14738839 | 0.82 | CYP3A4 (0.33) | — | |
| Bromide SCHEMBL19000 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL10714977 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4289662 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211256-B1 | Method for purifying fluoroaryl metal compound | NIPPON CATALYTIC CHEM IND (JP) | 2006-08-02 | — | — | EP | claimed |
| US-6509488-B2 | Magnesium halide is precipitated and removed from solution containing fluoroaryl metal compound, magnesium halide, and ether solvent, or magnesium halide is removed by treating solution with acid | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-01-21 | — | — | US | claimed |
| EP-1211256-A2 | Method for purifying fluoroaryl metal compound | Nippon Shokubai Co., Ltd. (JP) | 2002-06-05 | — | — | EP | claimed |
| US-20020065425-A1 | Method for purifying fluoroaryl metal compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-05-30 | — | — | US | claimed |
| US-12459904-B2 | Process for preparing carbamoyloxymethyl triazole cyclohexyl acid compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-04 | — | — | US | disclosed |
| US-20220298122-A1 | PROCESS FOR PREPARING CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACID COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2022-09-22 | — | — | US | disclosed |
| EP-3956312-A1 | PROCESS FOR PREPARING CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACID COMPOUNDS | Bristol-Myers Squibb Company (US) | 2022-02-23 | — | — | EP | disclosed |
| CN-113939502-A | Process for preparing carbamoyloxymethyltriazole cyclohexanoic acid compounds | 百时美施贵宝公司 | 2022-01-14 | — | — | CN | disclosed |
| WO-2020214545-A1 | PROCESS FOR PREPARING CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACID COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-10-22 | — | — | WO | disclosed |
| WO-2018115497-A1 | PROTEASOME INHIBITING ß-LACTAM PRODRUGS USEFUL FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISORDERS | VITA API (FR) | 2018-06-28 | — | — | WO | disclosed |
| CN-102011080-B | Low-melting-point and little-scum hot dipping auxiliary plating agent | UNIV KUNMING SCIENCE & TECHNOLOGY | 2012-06-20 | — | — | CN | disclosed |
| EP-1694684-B1 | PROCESS FOR MAKING CAMPTOTHECIN DERIVATIVES | BIONUMERIK PHARMACEUTICALS INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-0611773-A2 | Catalyst component for use in the polymerization of alpha-olefins and process for producing alpha-olefin polymers using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0611772-A2 | Catalyst component for use in the polymerization of alpha-olefins and process for producing alpha-olefin polymers using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0589638-A2 | Powder catalyst composition and process for polymerizing olefins with the use thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0500944-A1 | CATALYST FOR $g(a)-OLEFIN POLYMERIZATION AND PRODUCTION OF POLY-$g(a)-OLEFIN THEREWITH | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4366086-A | Composition containing chlorine, bromine and magnesium | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4349483-A | Process for the preparation of aluminum trihydrocarbyls | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4328123-A | COMPRISING AN ALUMINUM HYDROCARBYL, A SUPPORT FROM AN ORGANO MAGNESIUM COMPOUND AND AN SLUMINUM HALIDE, AND TITANIUM TETRACHLORIDE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-05-04 | — | — | US | disclosed |
| US-4321347-A | Process for the polymerization of olefins | GULF RESEARCH & DEVELOPMENT CO. (US) | 1982-03-23 | — | — | US | disclosed |