Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18749725 | 0.92 | MAPT (0.44) | FFAR4SLC22A12ALDH1A1TSHRMAPT | |
| SCHEMBL18515567 | 0.91 | SLC22A12 (0.41) | SLC22A12ALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL18515271 | 0.90 | MRGPRX4 (0.37) | FFAR4SLC22A12TSHRCD274 | |
| SCHEMBL18515554 | 0.90 | FFAR4 (0.35) | FFAR4SLC22A12ALDH1A1TSHRMEN1 | |
| SCHEMBL18515581 | 0.90 | SLC22A12 (0.45) | SLC22A12ALDH1A1MAPTRAB9ANPSR1 | |
| SCHEMBL18514424 | 0.88 | FFAR4 (0.39) | FFAR4SLC22A12ALDH1A1MAPTRAB9A | |
| SCHEMBL18514405 | 0.87 | FFAR4 (0.49) | FFAR4SLC22A12ALDH1A1MAPTRAB9A | |
| SCHEMBL18515570 | 0.87 | TSHR (0.40) | SLC22A12ALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL18515565 | 0.87 | SLC22A12 (0.38) | SLC22A12ALDH1A1MAPTRAB9ANPSR1 | |
| SCHEMBL18515562 | 0.87 | ANO1 (0.41) | SLC22A12ALDH1A1TSHRMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3130584-A1 | AROMATIC COMPOUND AND USES THEREOF | Sumitomo Chemical Company Limited (JP) | 2017-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | FFAR4 4194/4885SLC22A12 4063/4885ALDH1A1 1238/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | FFAR4 4026/4885SLC22A12 4001/4885ALDH1A1 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.