Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.75 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176294 | 0.91 | FOLH1 (0.86) | FOLH1DGAT1 | |
| SCHEMBL23710805 | 0.91 | FOLH1 (0.86) | FOLH1DGAT1 | |
| SCHEMBL18516752 | 0.91 | FOLH1 (0.86) | FOLH1DGAT1 | |
| SCHEMBL18516681 | 0.87 | FOLH1 (0.82) | FOLH1DGAT1 | |
| SCHEMBL18145415 | 0.85 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL22712935 | 0.85 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL14729344 | 0.85 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL16641923 | 0.83 | FOLH1 (0.69) | FOLH1DGAT1 | |
| SCHEMBL18516784 | 0.83 | FOLH1 (0.67) | FOLH1 | |
| SCHEMBL18516781 | 0.83 | FOLH1 (0.72) | FOLH1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027870-A1 | TRIAZOLE CONJUGATED UREAS, THIOUREAS, CARBAMATES, AND \"REVERSED\" CARBAMATES FOR PSMA-TARGETED IMAGING AGENTS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-16 | — | — | WO | disclosed |