Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777598 | 1.00 | PRCP (0.47) | PRCPHCRTR1HCRTR2 | |
| SCHEMBL15987143 | 0.89 | CYP3A4 (0.49) | — | |
| SCHEMBL2777214 | 0.88 | PRCP (0.53) | PRCPHCRTR1HCRTR2 | |
| SCHEMBL2777216 | 0.88 | PRCP (0.53) | PRCPHCRTR1HCRTR2 | |
| SCHEMBL12798462 | 0.88 | PRCP (0.53) | PRCPHCRTR1HCRTR2 | |
| SCHEMBL12422931 | 0.86 | PRCP (0.49) | PRCP | |
| SCHEMBL15045706 | 0.86 | PRCP (0.49) | PRCP | |
| SCHEMBL12422921 | 0.86 | PRCP (0.49) | PRCP | |
| SCHEMBL12422920 | 0.86 | PRCP (0.49) | PRCP | |
| SCHEMBL2780474 | 0.86 | PRCP (0.42) | PRCPHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318376-A1 | BI-1H-BENZIMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-05-11 | — | — | EP | claimed |
| WO-2010017401-A1 | BI-1H-BENZIMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-11 | — | — | WO | claimed |