Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12342815 | 0.84 | CA14 (0.53) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL18522116 | 0.84 | CA14 (0.48) | CA14ALOX5PTGS1PTGS2HDAC1 | |
| SCHEMBL18522357 | 0.82 | CA14 (0.43) | CA14ALOX5PTGS1PTGS2HDAC1 | |
| SCHEMBL25756500 | 0.82 | CA14 (0.43) | CA14ALOX5PTGS1PTGS2HDAC1 | |
| SCHEMBL25756499 | 0.80 | CA14 (0.78) | CA14 | |
| SCHEMBL18897657 | 0.79 | CA14 (0.50) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL24492212 | 0.79 | CA14 (0.51) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL18522120 | 0.78 | CA14 (0.40) | CA14ALOX5PTGS1PTGS2HDAC1 | |
| SCHEMBL25123419 | 0.78 | CA14 (0.44) | CA14ALOX5PTGS1PTGS2HDAC1 | |
| Hydrochloric Acid SCHEMBL18546738 | 0.77 | CYP1A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027721-A1 | NEAR-IR LIGHT-CLEAVABLE CONJUGATES AND CONJUGATE PRECURSORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-02-16 | — | — | WO | disclosed |