Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18525645 | 1.00 | IRAK4 (0.62) | IRAK4 | |
| SCHEMBL18497765 | 0.95 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL18497764 | 0.95 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL18497822 | 0.95 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL17148571 | 0.90 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL18497836 | 0.89 | CHEK2 (0.48) | IRAK4 | |
| SCHEMBL18497837 | 0.89 | CHEK2 (0.48) | IRAK4 | |
| SCHEMBL18497748 | 0.89 | IRAK4 (0.67) | IRAK4 | |
| SCHEMBL18497817 | 0.88 | CHEK2 (0.47) | IRAK4 | |
| SCHEMBL18497816 | 0.88 | CHEK2 (0.47) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |