SCHEMBL18525655

SCHEMBL18525655

CCCC1CCC(C)N1C

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16186008 1.00 CA1 (0.32) CA1CA2CA4
SCHEMBL21872396 0.86 CA1 (0.39) CA1CA2CA4
SCHEMBL25824908 0.86 CA1 (0.39) CA1CA2CA4
SCHEMBL19671149 0.86 CYP1A2 (0.37)
SCHEMBL18388628 0.86 SLC18A2 (0.39) CA1CA2CA4
SCHEMBL17853020 0.85 SLC18A2 (0.38) CA1CA2CA4
SCHEMBL13848575 0.85 SLC18A2 (0.38) CA1CA2CA4
SCHEMBL20280521 0.83 SLC18A2 (0.30)
SCHEMBL8318799 0.80
SCHEMBL17987158 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632443-B1 ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2023-06-07 EP disclosed
WO-2019134680-A1 INHIBITOR OF APOPTOSIS SIGNAL-REGULATING KINASE-1 AND APPLICATION THEREOF 广州市恒诺康医药科技有限公司 2019-07-11 WO disclosed
WO-2017025849-A1 BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS PFIZER INC. (US) 2017-02-16 WO disclosed