⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929760 | 0.84 | MANBA (0.32) | — | |
| SCHEMBL13623200 | 0.79 | EBP (0.39) | — | |
| SCHEMBL6436336 | 0.74 | — | — | |
| SCHEMBL14750532 | 0.68 | — | — | |
| SCHEMBL17917670 | 0.68 | — | — | |
| SCHEMBL17917649 | 0.68 | — | — | |
| SCHEMBL17917655 | 0.68 | — | — | |
| SCHEMBL18512448 | 0.67 | — | — | |
| SCHEMBL12191197 | 0.65 | — | — | |
| SCHEMBL12899591 | 0.65 | MANBA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044539-A1 | OLIGOMERIC COMPOUNDS COMPRISING ALPHA-BETA-CONSTRAINED NUCLEIC ACID | IONIS PHARMACEUTICALS, INC. (US) | 2017-02-16 | — | — | US | disclosed |