⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16868374 | 1.00 | — | — | |
| SCHEMBL2805443 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3032015 | 0.98 | NSD2 (0.39) | — | |
| SCHEMBL7123682 | 0.86 | NSD2 (0.38) | — | |
| SCHEMBL29954390 | 0.86 | NSD2 (0.38) | — | |
| SCHEMBL29955088 | 0.86 | NSD2 (0.38) | — | |
| SCHEMBL158602 | 0.85 | NSD2 (0.44) | — | |
| Hydrochloric Acid SCHEMBL2003747 | 0.83 | NSD2 (0.42) | — | |
| SCHEMBL3658341 | 0.79 | — | — | |
| SCHEMBL13012313 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118853310-A | Environment-friendly nano suspension cleaning agent and preparation method thereof | 洛阳泽铭清洗设备有限公司 | 2024-10-29 | — | — | CN | claimed |
| EP-2963026-B1 | SUBSTITUTED (R)-3-(4-METHYLCARBAMOYL-3-FLUOROPHENYLAMINO)TETRAHYDROFURAN-3-ENECARBOXYLIC ACID (VARIANTS) AND ESTER THEREOF, METHOD FOR PRODUCING AND USING SAME | R PHARM INT LLC (RU) | 2020-04-29 | — | — | EP | claimed |
| US-20160016925-A1 | Substituted (R)-3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-encarboxylic acid (variants) and ester thereof, method for preparation and use | Ivachtchenko, Alexandre Vasilievich (US) | 2016-01-21 | — | — | US | claimed |
| EP-2963026-A2 | SUBSTITUTED (R)-3-(4-METHYLCARBAMOYL-3-FLUOROPHENYLAMINO)TETRAHYDROFURAN-3-ENECARBOXYLIC ACID (VARIANTS) AND ESTER THEREOF, METHOD FOR PRODUCING AND USING SAME | Limited Liability Company "Avionco" (RU) | 2016-01-06 | — | — | EP | claimed |
| CN-105008340-A | Substituted (R) -3- (4-methylcarbamoyl-3-fluorophenylamino) tetrahydrofuran-3-carboxylic acid (variants) and esters thereof, method for the production and use thereof | LTD LIABILITY COMPANY AVIONCO AVIONCO LLC | 2015-10-28 | — | — | CN | claimed |
| EP-4727655-A1 | DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF | Mariana Oncology Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4729094-A2 | Modulators of complement activity | UCB Holdings, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727654-A1 | DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF | Mariana Oncology Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727653-A1 | DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF | Mariana Oncology Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4719381-A1 | LIGAND-POLAR DRUG CONJUGATES | Tripartite Therapeutics Inc. (TW) | 2026-04-08 | — | — | EP | disclosed |
| US-12558398-B2 | Inflammatory disease treatment with complement inhibitors | UCB HOLDINGS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| EP-4218790-B1 | MODULATORS OF COMPLEMENT ACTIVITY | UCB HOLDINGS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| CN-101573346-A | Synthesis method of 3-aminotetrahydrofuran-3-carboxylic acid derivative and application thereof as medicine | BOEHRINGER INGELHEIM INT (DE) | 2009-11-04 | — | — | CN | disclosed |
| US-7476663-B2 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-13 | — | — | US | disclosed |
| WO-2008080891-A2 | PROCESS FOR THE SYNTHESIS OF DERIVATIVES OF 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLIC ACID AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008080891-A2 | PROCESS FOR THE SYNTHESIS OF DERIVATIVES OF 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLIC ACID AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| US-20060035883-A1 | Novel serotonin receptor ligands and their uses thereof | OMEROS CORPORATION | 2006-02-16 | — | — | US | disclosed |
| US-20050277628-A1 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |