Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 6/20 | 0.37 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | INPP5B | P32019 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528450 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2INPPL1INPP5AAKT1 | |
| SCHEMBL18528463 | 0.96 | INPPL1 (0.36) | PTGS1PTGS2INPPL1INPP5AAKT1 | |
| SCHEMBL18528464 | 0.96 | INPPL1 (0.36) | PTGS1PTGS2INPPL1INPP5AAKT1 | |
| SCHEMBL17224365 | 0.91 | INPPL1 (0.36) | PTGS1PTGS2INPPL1INPP5AAKT1 | |
| SCHEMBL17224367 | 0.91 | INPPL1 (0.36) | PTGS1PTGS2INPPL1INPP5AAKT1 | |
| SCHEMBL17224375 | 0.87 | PTGS1 (0.44) | PTGS1PTGS2INPPL1INPP5AAKT1 | |
| SCHEMBL17224381 | 0.80 | PTGS1 (0.51) | PTGS1PTGS2CYP1A2MEN1GAA | |
| SCHEMBL17224380 | 0.80 | PTGS1 (0.51) | PTGS1PTGS2CYP1A2MEN1GAA | |
| SCHEMBL17224331 | 0.79 | PTGS1 (0.47) | PTGS1PTGS2HTR3EHTR3BHTR3A | |
| SCHEMBL17224330 | 0.79 | PTGS1 (0.47) | PTGS1PTGS2HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | claimed |
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | disclosed |