⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834814 | 0.74 | — | — | |
| SCHEMBL10354209 | 0.74 | — | — | |
| SCHEMBL165533 | 0.70 | — | — | |
| SCHEMBL9641464 | 0.67 | — | — | |
| SCHEMBL25381363 | 0.67 | — | — | |
| SCHEMBL8824459 | 0.67 | — | — | |
| SCHEMBL12184003 | 0.65 | — | — | |
| SCHEMBL9666569 | 0.65 | IDO1 (0.36) | — | |
| SCHEMBL14546345 | 0.62 | — | — | |
| SCHEMBL11176776 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848968-B | Process for preparing lactams from glyoxylic acid | 荷兰联合利华有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3337785-B1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2020-03-18 | — | — | EP | disclosed |
| US-10377707-B2 | Process for the preparation of lactams from glyoxalic acid | CONOPCO INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20180237388-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYCOXYLIC ACID | Conopco, Inc., a/b/a UNILEVER (US) | 2018-08-23 | — | — | US | disclosed |
| EP-3337785-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | Unilever PLC (GB) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017029104-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2017-02-23 | — | — | WO | disclosed |