Verbalactone

Verbalactone

SCHEMBL18529435

CCCCC[C@@H]1C[C@@H](O)CC(=O)O[C@H](CCCCC)C[C@@H](O)CC(=O)O1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.61
CYP1A2 P05177 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679531 1.00 PPARG (0.61) PPARGCYP1A2
SCHEMBL9681220 1.00 PPARG (0.61) PPARGCYP1A2
SCHEMBL9679475 1.00 PPARG (0.61) PPARGCYP1A2
SCHEMBL9420002 1.00 PPARG (0.61) PPARGCYP1A2
SCHEMBL9680026 1.00 PPARG (0.61) PPARGCYP1A2
SCHEMBL3802765 0.98 PPARG (0.63) PPARGCYP1A2
SCHEMBL3796111 0.98 PPARG (0.63) PPARGCYP1A2
SCHEMBL28452647 0.98 PPARG (0.63) PPARGCYP1A2
SCHEMBL12798079 0.95 PPARG (0.55) PPARGCYP1A2
SCHEMBL12798082 0.95 PPARG (0.55) PPARGCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12122994-B2 Methods for fermentative production of massoia lactone TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2024-10-22 US disclosed
US-20230365915-A1 METHODS FOR FERMENTATIVE PRODUCTION OF MASSOIA LACTONE TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2023-11-16 US disclosed
US-11639492-B2 Methods for fermentative production of massoia lactone TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2023-05-02 US disclosed
EP-3337889-B1 METHODS FOR FERMENTATIVE PRODUCTION OF MASSOIA LACTONE TEMASEK LIFE SCIENCES LABORATORY LTD (SG) 2023-04-26 EP disclosed
US-20200157488-A1 METHODS FOR FERMENTATIVE PRODUCTION OF MASSOIA LACTONE TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2020-05-21 US disclosed
US-20190010444-A1 METHODS FOR FERMENTATIVE PRODUCTION OF MASSOIA LACTONE TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2019-01-10 US disclosed
EP-3337889-A1 METHODS FOR FERMENTATIVE PRODUCTION OF MASSOIA LACTONE Temasek Life Sciences Laboratory Limited (SG) 2018-06-27 EP disclosed
WO-2017030503-A1 METHODS FOR FERMENTATIVE PRODUCTION OF MASSOIA LACTONE TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2017-02-23 WO disclosed