SCHEMBL185316

SCHEMBL185316

C=Cc1cnc(NC(=O)C(OC2CCOCC2)c2ccc(S(=O)(=O)N3CCOCC3)cc2)s1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184597 0.89 GCK (0.69) GCK
SCHEMBL185059 0.88 GCK (1.00) GCK
SCHEMBL184905 0.86 GCK (0.75) GCK
SCHEMBL185118 0.83 GCK (0.90) GCK
SCHEMBL184507 0.80 GCK (0.75) GCK
SCHEMBL185002 0.79 GCK (0.73) GCK
SCHEMBL184453 0.77 GCK (1.00) GCK
SCHEMBL184609 0.77 GCK (0.64) GCK
SCHEMBL184398 0.77 GCK (0.80) GCK
SCHEMBL184416 0.76 GCK (0.62) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2402327-B1 Acetamide compounds as glucokinase activators, their process and medicinal applications IMPETIS BIOSCIENCES LTD (IN) 2018-03-07 EP disclosed
EP-2402327-A1 Acetamide compounds as glucokinase activators, their process and medicinal applications Advinus Therapeutics Private Limited (IN) 2012-01-04 EP disclosed