Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18533692 | 0.87 | KMT2A (0.41) | KMT2ARAB9AADORA2AADORA1SCN9A | |
| SCHEMBL14947217 | 0.87 | KMT2A (0.39) | KMT2ARAB9AADORA2AADORA1SCN9A | |
| SCHEMBL19151228 | 0.70 | KMT2A (0.53) | KMT2ARAB9ASCN9AHPGDSALDH1A1 | |
| SCHEMBL15806425 | 0.69 | KMT2A (0.52) | KMT2ARAB9ASCN9AHPGDSALDH1A1 | |
| SCHEMBL17612729 | 0.67 | PDK2 (0.36) | KMT2ARAB9ASCN9AHPGDSALDH1A1 | |
| SCHEMBL10033207 | 0.67 | BRD4 (0.36) | KMT2ARAB9ASCN9AALDH1A1MEN1 | |
| SCHEMBL18932729 | 0.67 | BRD4 (0.36) | KMT2ARAB9ASCN9AALDH1A1MEN1 | |
| SCHEMBL18533579 | 0.66 | KMT2A (0.34) | KMT2ARAB9AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL18344266 | 0.63 | ALK (0.40) | KMT2ARAB9ASCN9AMEN1SMN1; SMN2 | |
| SCHEMBL30229597 | 0.63 | ALK (0.40) | KMT2ARAB9ASCN9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931754-B1 | HEAVY GOODS VEHICLE TYRE COMPRISING A TREAD BASED ON A MODIFIED POLYISOPRENE, PROCESS FOR PREPARING SAME | MICHELIN & CIE (FR) | 2017-02-22 | — | — | EP | disclosed |