SCHEMBL18534331

SCHEMBL18534331

CC(C)(C)OC(=O)NC[C@H]1CC[C@H](NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.52
PBK Q96KB5 1/20 0.49
KMT2A Q03164 1/20 0.49
DRD2 P14416 6/20 0.48
BTK Q06187 1/20 0.48
ACACB O00763 5/20 0.47
ACACA Q13085 3/20 0.46
KDM1A O60341 1/20 0.45
MAOB P27338 1/20 0.45
CTSK P43235 2/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6154180 0.91 KMT2A (0.50) EPHX1PBKKMT2ADRD2BTK
SCHEMBL19762295 0.91 EPHX1 (0.50) EPHX1PBKKMT2ADRD2ACACB
SCHEMBL4921002 0.91 KMT2A (0.50) EPHX1PBKKMT2ADRD2BTK
SCHEMBL4920988 0.91 KMT2A (0.50) EPHX1PBKKMT2ADRD2BTK
SCHEMBL13135484 0.91 KMT2A (0.47) EPHX1PBKKMT2ADRD2BTK
SCHEMBL6850326 0.91 KMT2A (0.50) EPHX1PBKKMT2ADRD2BTK
SCHEMBL4377073 0.90 KMT2A (0.56) EPHX1KMT2ADRD2ACACBACACA
SCHEMBL3942686 0.90 KMT2A (0.56) EPHX1KMT2ADRD2ACACBACACA
SCHEMBL3816616 0.90 KMT2A (0.56) EPHX1KMT2ADRD2ACACBACACA
SCHEMBL190838 0.90 KMT2A (0.56) EPHX1KMT2ADRD2ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2881417-B1 POLYAMIDE ACID RESIN COMPOSITION, POLYIMIDE FILM USING SAME, AND METHOD FOR PRODUCING SAID POLYIMIDE FILM TORAY INDUSTRIES (JP) 2017-02-22 EP disclosed