Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 16/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184483 | 0.85 | CYP4F2 (0.47) | ATRCYP4F2CYP4A11 | |
| SCHEMBL29212475 | 0.81 | CYP4F2 (0.47) | ATRCYP4F2CYP4A11 | |
| SCHEMBL15509064 | 0.80 | CYP4F2 (0.47) | ATRCYP4F2CYP4A11 | |
| SCHEMBL18985877 | 0.79 | CYP4F2 (0.50) | ATRCYP4F2CYP4A11 | |
| SCHEMBL13736084 | 0.77 | CYP4F2 (0.54) | ATRCYP4F2CYP4A11 | |
| SCHEMBL25831182 | 0.77 | CYP4F2 (0.47) | ATRCYP4F2CYP4A11 | |
| SCHEMBL16389155 | 0.75 | CYP4F2 (0.55) | ATRCYP4F2CYP4A11 | |
| SCHEMBL25378387 | 0.75 | CYP4F2 (0.47) | ATRCYP4F2CYP4A11 | |
| SCHEMBL30509961 | 0.75 | CYP4F2 (0.50) | ATRCYP4F2CYP4A11 | |
| SCHEMBL25262023 | 0.75 | CYP4F2 (0.50) | ATRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909212-B1 | SUBSTITUTED 1,4-DIHYDROPYRAZOLO[4,3-B]INDOLES | TAKEDA PHARMACEUTICALS CO (JP) | 2017-02-22 | — | — | EP | disclosed |