SCHEMBL18536741

SCHEMBL18536741

OC[C@@H]1CCC(Cc2ccccc2)O1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.64
SLC6A4 P31645 2/20 0.64
SLC6A3 Q01959 2/20 0.64
GBA1 P04062 1/20 0.44
ALPL P05186 1/20 0.44
ALPI P09923 1/20 0.44
ALPG P10696 1/20 0.44
CYP2A6 P11509 1/20 0.42
GRM2 Q14416 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DRD1 P21728 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18678099 1.00 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3GBA1ALPL
SCHEMBL2690346 0.81 SLC6A2 (0.74) SLC6A2SLC6A4SLC6A3ALPLALPI
SCHEMBL2691450 0.81 SLC6A2 (0.64) SLC6A2SLC6A4SLC6A3GBA1ALPL
SCHEMBL31412815 0.79 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3GBA1CYP2A6
SCHEMBL12075097 0.78 SLC6A2 (0.70) SLC6A2SLC6A4SLC6A3GBA1ALPL
SCHEMBL2691374 0.78 SLC6A4 (1.00) SLC6A2SLC6A4SLC6A3ALPLALPI
SCHEMBL20231377 0.78 HRH4 (0.56) SLC6A2SLC6A4SLC6A3GBA1DRD1
SCHEMBL20234410 0.78 HRH4 (0.56) SLC6A2SLC6A4SLC6A3GBA1DRD1
SCHEMBL10445179 0.78 HRH4 (0.56) SLC6A2SLC6A4SLC6A3GBA1DRD1
SCHEMBL6664494 0.77 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3GBA1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2859008-B1 MODIFIED OLIGONUCLEOTIDES COMPRISING THIOL FUNCTIONS AND THE USE OF SAME FOR THE DETECTION OF NUCLEIC ACIDS ETABLISSEMENT FRANÇAIS DU SANG (EFS) (FR) 2017-02-22 EP disclosed